High density lipoprotein – quality and function

High density lipoprotein--quality and function.

Introduction Atherosclerosis is a focal disease of the large and medium sized arteries in areas of disturbed blood flow caused by endothelial injury, dysfunction and local inflammation [1]. Coronary heart disease (CHD) is the most common cause of death in western countries and in developing countries it accounts for over 4.5 million deaths annually [2]. Dyslipidaemia has been identified as a ma...

High density Lipoprotein; What to Measure: Quality or Quantity?

High-Density Lipoprotein Function

Although high-density lipoproteins (HDL) possess many features that contribute to the association between elevated HDL cholesterol and protection from atherosclerosis, these lipoproteins may be modified in certain individuals and/or circumstances to become proinflammatory. The ability of HDL to inhibit or paradoxically to enhance vascular inflammation, lipid oxidation, plaque growth, and thromb...

The role of level and function of High Density Lipoprotein (HDL) in Cardiovascular Diseases

High-density lipoprotein (HDL) is a set of particles with heterogeneous structures that have different functions due to various compounds including surface charge, size, lipid, and protein compounds. Several prospective epidemiological studies have demonstrated that there is a clear inverse relationship between serum HDL concentration and risk of coronary heart disease, despite this relationshi...

high density lipoprotein; what to measure: quality or quantity?

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